Friday, May 21, 2010

Exercise Can Overcome Obesity Gene

Overcome Obesity Gene - Research Shows Physical Activity Can Lower genetic predisposition toward obesity

By Caroline Wilbert
WebMD Health News

Sept. 8, 2008 - Though genetics plays a role in obesity, new research shows that regular physical activity can blunt the effects of genetic predisposition to become obese.

Various specific genes, known as a gene regulator of fat mass and obesity associated (FTO), was widely understood to have the relationship of body mass index, based on the background material of this study, published in the Archives of Internal Medicine.

Evadnie Rampersaud, MSPH, PhD, who is from the University of Maryland University School of Medicine and now the University of Miami, along with fellow analyzing how lifestyle affects weight person who has a genetic predisposition to become obese

Researchers analyzed DNA samples from 704 healthy adults, collected between 2003 and 2007. Participants also undergo psychological tests, including measurement of physical activity using an accelerometer, which bears the participants in their bodies for a week. This instrument measures participants' level of activity with intervals of 15 seconds.

The average participant age of 44 years; 53% of men. 44 percent of men are overweight (BMI 23 kg/m2 - 25 kg/m) and 10% obese (BMI> 25 kg/m2). Overwight Approximately 64% of women and 31% obese.

The group was divided into groups with high levels of activity and low. In the group with high activity to burn 900 calories more per day compared with the group with low activity. According to the researchers was the same as moderately intense physical activity (brisk walking, gardening, or cleaning the house) for three to four hours

Research also shows, as has been done by previous researchers, that a person with certain FTO gene variation tended to be overweight. However, researchers have found that although genetic terpredisposisi to become obese, this gene has no effect whatever on those who have a physical activity is well above average.

Since obesity had become a global health concern, an understanding of every aspect of the FTO gene is important, the researchers said. Variants of FTO gene are often found - about 30% of the population of Europe has a variant, according to this study. Genetic variation associated with obesity risk is 20% larger, write the researchers.

Authored the study concluded, "These findings emphasize the important role of physical activity in health policy efforts to combat obesity, especially in someone who is genetically at risk.


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